Inhalt

•  
   Zusammenfassung
•  
   Abstract
•  
   Introduction
•  
  Theoretical Background
•  
  Radiotracers in Plant Biology
•  
   Transport System of Plants
•  
   PET Measurements of Plants
•  
   Radioactive Decay
•  
   Statistical Properties
•  
  Interaction of Particles with Matter
•  
   Interaction of Positrons and Electrons with Matter
•  
   Photons in Matter
•  
   Attenuation of Photons
•  
   Isotopes for Quantification and Radiotracers for Experiments with Plants
•  
  Detector Working Principles
•  
   Inorganic Scintillator
•  
   Silicon Photo Multipliers
•  
   Coincidence Detection and Classification
•  
   True Coincidences
•  
   Scattered Coincidences
•  
   Random Coincidences
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   Multiple Coincidences
•  
  Tomographic Image Reconstruction
•  
   Analytical Image Reconstruction
•  
   Iterative Image Reconstruction
•  
   Correction for Quantitative Imaging
•  
  phenoPET Setup
•  
   General Setup
•  
   Detector Setup
•  
   Digital Photon Counter and Crystal Matrix
•  
   Concentrator Board
•  
  phenoPET Operation
•  
   phenostore
•  
   DPCShell
•  
   Graphical User Interface
•  
   Improvements due to the Redesign of the Firmware
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  Data Organization and Preparation for Image Reconstruction
•  
   Software Framework
•  
   Configuration Files
•  
   Structure of List Mode Files and Event Structure
•  
   Clustering and Calibration
•  
   Coincidence Sorting
•  
   Control Plots of Measured Data
•  
  Image Reconstruction with PET Reconstruction Software Toolkit
•  
   System Matrix
•  
   Sensitivity Model
•  
   Random Variance Reduction
•  
   Setup for Simulation with OpenGate
•  
  Rotation System
•  
   Setup of Intermediate System
•  
   Setup of Rotation System of the Lifting Table
•  
   Confirmation of Orbiting Frequency
•  
   Coincidence Sorting and Delayed Coincidences
•  
  Sorting Algorithms
•  
   General Software Structure
•  
   Handling of Multiple Coincidences
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   phenoSorter: A Sector Based Coincidence Sorter
•  
   phenoGateSorter: Adaptations to the OpenGate Coincidence Sorter
•  
   Characterization with Simulated Data
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   Method
•  
   Results of NEMA Rat Size Scatter Phantom
•  
   Characterization with a Decay Experiment
•  
   Measurement Setup
•  
   Analysis
•  
   Results of Decay Experiment
•  
   Comparison of the Different Sorting Strategies
•  
   Possible Improvements and Further Investigations
•  
   Count Rate Corrections
•  
   Correction Model
•  
   Application of the Correction Factors in the Iterative Image Reconstruction
•  
   Setup for Determination of Count Rate Corrections
•  
   Determination of Correction Factors
•  
   Correction of Dropped and Missing Frames
•  
   Dead Time Analysis of Measured Single Events
•  
   Dead Time Analysis of Coincidence Count Rates
•  
  Resulting Correction Factors
•  
   Frame Dropping
•  
   Dead Time Correction Factors for Singles
•  
   Coincidence Dead Time Correction Factors for Module Combinations
•  
   Coincidence Dead Time Correction Factor of Total Head Curve
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   Validation of Dead Time Correction Factors and Investigation of Position Dependence
•  
   Comparison of Dead Time Correction Factors of Modules
•  
   Comparison of Coincidence Dead Time
•  
   Discussion
•  
  Normalization
•  
   Implemented Normalization Model
•  
   Iteration Schema and Starting Values
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  Test with Synthetic Data
•  
   Method
•  
   Influence of Geometric Sensitivity Widths
•  
   Influence of Overall Statistics
•  
   Normalization with a Rotating Rod Source
•  
   Measurement Setup
•  
   Preparation of Measured Data
•  
   Calculation of Expectation Values
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   Localization of the Normalization Phantom
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   Comparison of Normalization Factors
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   Homogenity of Normalized Data
•  
   Influences of Expectation Values
•  
   Discussion of Expectation Values
•  
   Discussion
•  
  Correction of Photon Interaction with Plants and Their Soil
•  
  Measurement of Attenuation Coefficients
•  
   Transmissions Reconstruction Algorithm
•  
   Blank Measurement for Reconstruction
•  
   Acquisition of Transmission Measurements
•  
   Correction of Transmission Source Decay
•  
   Influence of Radiation from Detector Crystals on Blank Data
•  
   Reproducibility of Rod Source Positioning
•  
   PRESTO Scatter Simulation
•  
   Simulation Procedure and Setup for phenoPET
•  
   Scatter Estimates for Image Reconstruction
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   Sensitivities for Scaling of Scattered Coincidences
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   Influence and Correction of Compton Scattering on Transmission Reconstruction
•  
   Simulation Setup and Data Analysis
•  
   Results
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   Discussion
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   Measurement Setups for Investigation of Image Quality
•  
  Transmission Reconstruction of Measurements with Scatter Correction
•  
   Image Reconstruction and Estimation of Scatter Correction
•  
   Evaluation of Attenuation Maps
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   Results
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   Discussion
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   Analysis of Emission Data
•  
   Convergence of Iterative Scatter Correction
•  
   Effect of Attenuation Maps on Scatter Correction
•  
   Discussion
•  
  Calculation of Calibration Factors
•  
   Method
•  
   Results
•  
   Discussion
•  
  Simulation Duration and Effect of Multiplexing
•  
   Method
•  
   Results
•  
   Outlook
•  
  Attenuation Coefficients of Different Soil Types and Hydroponics
•  
   Experimental Setup
•  
   Results
•  
   Discussion
•  
  Dependency of Attenuation on Water Uptake During a Measurement
•  
   Method
•  
   Results
•  
   Discussion
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   Conclusion and Outlook
•  
  Validation of Performance and Operation Stability
•  
  Temperature Stability
•  
   Temperature Behavior for Constant Activity Distributions
•  
   Temperature Behavior During a Dynamic Measurements
•  
   Consequences for Routine Operation
•  
  Performance in a Dynamic Measurement
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   Measurement Setup, Data Processing and Image Reconstruction
•  
   Stability over Dynamic Range
•  
   Signal-To-Noise with Noise-Equivalent Count Rates
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  Spatial Resolution
•  
   Phantom Preparation and Measurement
•  
   Results
•  
   Discussion
•  
   Summary
•  
   Conclusion and Outlook
•  
   Bibliography
•  
   Acronyms
•  
   Notation
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   Glossary
•  
   List of Figures
•  
   List of Tables
•  
   Acknowledgements
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   Quality of Fits: Residual Graphs and Pull Distributions
•  
  Convergence of Transmission Reconstruction
•  
  Relaxation Parameter and Number of Iterations
•  
   Method
•  
   Results and Discussion
•  
   Duration of Transmission Measurements
•  
   Method
•  
   Results and Discussion
•  
   Outlook